Cosmetic & skin-signalling peptides
Collagen Peptides
Also known as collagen hydrolysate · hydrolysed collagen · bioactive collagen peptides
Enzymatically hydrolysed collagen taken orally, studied in randomised trials for skin, joint and bone outcomes.
In 60 seconds
Food supplement with multiple small randomised trials in skin ageing, activity-related knee pain and postmenopausal bone density. Trials report it as well tolerated.
- A randomised trial measured wrinkle volume and dermal matrix markers with oral collagen peptides.
- A randomised trial measured bone mineral density and bone markers in postmenopausal women.
- In 139 athletes with functional knee pain, collagen peptides were tested against placebo.
Mechanism
Small collagen-derived di- and tripeptides (e.g. prolyl-hydroxyproline) are absorbed and proposed to signal fibroblasts and chondrocytes to increase matrix synthesis.
Research status
Food supplement with multiple small randomised trials in skin ageing, activity-related knee pain and postmenopausal bone density.
Key studies
A randomised trial measured wrinkle volume and dermal matrix markers with oral collagen peptides.
Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis — Skin Pharmacol Physiol, 2014 · PMID 24401291
A randomised trial measured bone mineral density and bone markers in postmenopausal women.
Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women-A Randomized Controlled Study — Nutrients, 2018 · PMID 29337906
In 139 athletes with functional knee pain, collagen peptides were tested against placebo.
Improvement of activity-related knee joint discomfort following supplementation of specific collagen peptides — Appl Physiol Nutr Metab, 2017 · PMID 28177710
Reviews collagen hydrolysate evidence in osteoarthritis and joint disorders.
Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature — Curr Med Res Opin, 2006 · PMID 17076983
Safety signals in the literature
Trials report it as well tolerated.
Legal status (South Africa)
Cosmetic-ingredient peptides; research use only in the form we would supply.
Related compounds we stock
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Comparisons
Questions
What is Collagen Peptides?
Enzymatically hydrolysed collagen taken orally, studied in randomised trials for skin, joint and bone outcomes. Small collagen-derived di- and tripeptides (e.g. prolyl-hydroxyproline) are absorbed and proposed to signal fibroblasts and chondrocytes to increase matrix synthesis.
What is the research status of Collagen Peptides?
Food supplement with multiple small randomised trials in skin ageing, activity-related knee pain and postmenopausal bone density.
What safety signals are reported for Collagen Peptides?
Trials report it as well tolerated.
Does Living Water Labs stock Collagen Peptides?
Not at present. Collagen Peptides is profiled here for reference, with citations to the published literature. You can ask to be notified if we add it. Cosmetic-ingredient peptides; research use only in the form we would supply.
More in Skin peptides
Research reference only. This page summarises published literature; it is not medical advice and contains no guidance on human use. Products supplied by Living Water Labs are for laboratory research only.






