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◂ RESEARCH LIBRARY
Retatrutide Pen research peptide

Research Overview

Retatrutide Pen

Effortless Fat Loss

HPLC-verified 98%Batch CoAResearch use only

AVAILABLE SIZES

30 mg60 mg

OVERVIEW

Retatrutide Pen (Effortless Fat Loss) is a research-grade peptide supplied by Living Water Labs for laboratory investigation. Next-generation triple-action peptide for accelerated fat loss and metabolic reset. Each batch is HPLC-verified to a minimum 98% purity with a batch-specific Certificate of Analysis. The summary below outlines documented mechanisms and study areas reported in the research literature.

Scientific name

LY3437943 (GLP-1/GIP/Glucagon Receptor Triagonist)

Molecular weight

4735.5 g/mol

Purity

98.7%

Vial size

30mg

DOCUMENTED RESEARCH AREAS

  • Pre-filled, pre-reconstituted — ready to use
  • Powerful appetite control
  • Accelerated fat loss
  • Sharper blood sugar balance
  • All-day satiety
  • Advanced metabolic optimisation

MECHANISM OF ACTION

Retatrutide (LY3437943) is a single peptide engineered to activate three receptors at once — GLP-1, GIP and glucagon. Research describes this triple-agonism combining appetite and glucose effects (GLP-1/GIP) with increased energy expenditure (glucagon), and it is being evaluated in clinical trials for metabolic endpoints.

  • Single peptide agonist at GLP-1, GIP and glucagon receptors
  • Glucagon component studied for increased energy expenditure
  • Evaluated in phase-2 clinical trials for weight and metabolic endpoints

STUDY SUMMARIES

3 peer-reviewed references

N Engl J Med · 2023

Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial

In a phase-2 randomised trial, participants receiving retatrutide showed dose-dependent reductions in body weight over 48 weeks.

View on PubMed (PMID 37366315)

Nat Med · 2024

Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial

A phase-2a randomised trial reported reductions in liver fat in participants with metabolic-dysfunction-associated steatotic liver disease.

View on PubMed (PMID 38858523)

NPJ Metab Health Dis · 2025

Incretin triple agonist retatrutide (LY3437943) alleviates obesity-associated cancer progression

A preclinical study examining retatrutide effects in obesity-associated cancer-progression models.

View on PubMed (PMID 40094000)

CITATIONS

  1. 1.Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial. N Engl J Med. 2023. PMID 37366315. pubmed.ncbi.nlm.nih.gov/37366315
  2. 2.Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial. Nat Med. 2024. PMID 38858523. pubmed.ncbi.nlm.nih.gov/38858523
  3. 3.Incretin triple agonist retatrutide (LY3437943) alleviates obesity-associated cancer progression. NPJ Metab Health Dis. 2025. PMID 40094000. pubmed.ncbi.nlm.nih.gov/40094000

Citations describe findings reported in the referenced preclinical, in-vitro or clinical literature. They are provided for research and educational purposes only and are not a therapeutic claim.

All information is provided for research and educational purposes only and describes findings in preclinical/in-vitro literature. Not medical advice. Products are supplied strictly for research purposes — not for human consumption.

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