Research peptides for cycling & triathlon in South Africa
Endurance sport in South Africa, the Cape Epic, 94.7, Ironman African Championship, has a long and uncomfortable relationship with the peptide literature, because the erythropoiesis research that defined doping in the 1990s is peptide research. Coaches, physiologists and the riders themselves read this literature knowing exactly where it leads.
This page covers it honestly: mitochondrial-density and AMPK research, the oxygen-transport and tissue-protection literature that grew out of EPO biology, and the redox and recovery work. It names the compounds, grades the evidence and states the anti-doping status. The compounds are supplied for laboratory research only, and nothing here is for a competitor.
Mitochondrial research is the endurance scientist's home ground. MOTS-c activates AMPK, increases exercise capacity in mice and rises in plasma after acute exercise in humans; SS-31 binds cardiolipin and preserves ATP output under ischaemic stress; NAD+ is the cofactor behind sirtuin-mediated mitochondrial biogenesis. These are the mechanisms behind the adaptations that training produces, studied directly.
Oxygen transport is the sensitive literature. Erythropoietin sustains red-cell production through its receptor and JAK2, and its prohibition in sport is one of the founding events of modern anti-doping. The newer research is non-haematopoietic: ARA-290 is an EPO-derived peptide designed to act on the tissue-protective innate repair receptor without raising red-cell mass, studied in kidney injury and corneal nerve regrowth. Reading both halves is how an endurance physiologist understands the field.
AMPK and exercise capacity in mice
Cardiolipin and ATP recovery under hypoxia
NAD+ and mitochondrial biogenesis
Erythropoiesis and the Prohibited List
Non-haematopoietic EPO-receptor peptides
Oxidative stress after prolonged exercise
Compounds that recur in this literature
Research context only — what each compound has been studied for in published work, not what it does for anyone. Independently tested by Janoshik Analytical.
MOTS-c
Research vial
The mitochondrial peptide studied in mice for AMPK activation and increased exercise capacity, with human plasma levels that rise after exercise. The closest thing to an endurance-physiology peptide in the literature.
The cardiolipin-binding peptide that preserved cristae structure and speeded ATP recovery in ischaemic models, now with a human regulatory approval in a rare mitochondrial disease.
An EPO-derived peptide engineered to act on the innate repair receptor without the haematopoietic effect. Studied in kidney ischaemia-reperfusion and in a phase 2b corneal nerve-fibre trial; the non-doping half of EPO biology.
Endurance communities cluster in Cape Town, Stellenbosch, Johannesburg and Durban, all one to two business days from our Johannesburg hub with The Courier Guy, and Gauteng is usually next day. Weekday orders paid before noon dispatch the same afternoon. Lyophilised vials travel without a cold chain. A Courier Guy PUDO locker suits anyone training mid-morning. Free shipping over R2,500, Janoshik certificate linked on each product page.
EPO is listed on the site for laboratory research with its own research page. It is prohibited in sport and is not discussed on this page beyond its place in the literature.
Is MOTS-c prohibited?
Compounds not approved for human use fall under the Prohibited List's catch-all. A competing athlete should assume yes and consult their federation.
What is ARA-290?
A peptide derived from the EPO helix B region, designed to engage the tissue-protective receptor without raising haematocrit. It is studied in kidney injury, neuropathy and corneal nerve regrowth.
What does the certificate cover?
Compound identity and HPLC purity on an independent Janoshik Analytical report.
Educational content — not medical advice. All products supplied for research purposes only. Not for human consumption.
Research Axes · 22 Goals
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