Autophagy
Also known as: cellular recycling · self-eating
The cell’s self-cleaning recycling process; enhancing it is a recurring theme in longevity and metabolic research.
Autophagy ("self-eating") is the process by which a cell breaks down and recycles its own damaged components — misfolded proteins, worn-out organelles — reusing the parts. It keeps cells clean and functional.
Autophagy declines with age, and boosting it is a recurring goal of longevity research, linked to pathways such as AMPK activation and fasting-mimetic signalling that several research compounds are studied for.
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RELATED TERMS
AMPK
The cell’s master energy sensor; its activation is a key mechanism studied for MOTS-c and metabolic research compounds.
Sirtuin
A family of NAD+-dependent enzymes tied to ageing, DNA repair and metabolism — central to NAD+ longevity research.
Apoptosis
Programmed cell death — an orderly self-destruct that clears damaged cells; targeted by senolytic peptide research.
Mitochondria
The cell’s energy-producing organelles; their function is central to cellular-energy and longevity research.
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