FOXO4-DRI
Also known as: FOXO4 D-Retro-Inverso · FOXO4-DRI peptide · senolytic peptide
A designed peptide (FOXO4 D-Retro-Inverso) studied as a senolytic — selectively clearing senescent "zombie" cells in ageing research.
FOXO4-DRI is a synthetic peptide built using D-amino acids in a retro-inverso design, which makes it highly resistant to enzymatic breakdown. It is studied as a senolytic — an agent that selectively triggers apoptosis in senescent cells.
Senescent ("zombie") cells accumulate with age and secrete inflammatory signals; clearing them is a major theme of longevity research. FOXO4-DRI is one of the most-cited peptide tools in that senolytic literature.
Handled strictly for research purposes only.
ON THIS SITE
RELATED TERMS
Apoptosis
Programmed cell death — an orderly self-destruct that clears damaged cells; targeted by senolytic peptide research.
D- and L-Amino Acids
Amino acids come in mirror-image L and D forms; swapping in D-residues can make a peptide far more stable to enzymes.
Telomere / Telomerase
Protective caps on chromosome ends (telomeres) and the enzyme that extends them (telomerase) — central to longevity research.
Oxidative Stress
Cellular damage from an excess of reactive oxygen species — the imbalance antioxidants and many longevity compounds target.
Educational content, not medical advice. All products supplied for research purposes only — not for human consumption.