CLINICS & PRACTITIONERS · FUNCTIONAL MEDICINE

Research peptides for functional-medicine practitioners in South Africa

Functional-medicine practitioners read across systems rather than within one, and peptide research rewards that habit. The same compound appears in a gut-barrier paper, a neuroinflammation paper and a wound-healing paper, and the practitioner who follows the mechanism across all three understands the literature better than a specialist who reads only one.

This page is organised the way a functional-medicine reader thinks: by axis. Gut-immune, stress and HPA, redox and mitochondria, and the GH/IGF-1 axis each get their literature summarised and their recurring compounds named. The evidence is graded honestly, most of it preclinical. Nothing here is a protocol, and the compounds are supplied for laboratory research only.

What this field's literature looks at

On the gut-immune axis, BPC-157 and KPV dominate the animal literature: cytoprotection, mucosal-barrier restoration and NF-κB suppression in colitis models. Selank adds the immune-cytokine thread, with IL-6 and interferon modulation measured in animals and stress physiology measured in Russian human studies. On the stress axis, Selank and Semax come out of a clinical pharmacology tradition in which they are registered medicines, which gives them human data most research peptides lack.

On redox and mitochondria, glutathione has human trials showing raised stores from liposomal forms, SS-31 binds cardiolipin and preserves ATP output in injury models, MOTS-c activates AMPK in mouse metabolism, and NAD+ sits under the sirtuin and PARP enzymes. On the GH/IGF-1 axis, secretagogues and GHRH analogues are studied for pulsatile GH release, slow-wave sleep and connective-tissue turnover. Hormone-class and incretin compounds have their own pages and are not detailed here.

  • Gut-immune axis and mucosal barrier
  • HPA axis and stress neuropeptides
  • Glutathione and redox status
  • Cardiolipin-binding mitochondrial peptides
  • NAD+, sirtuins and DNA repair
  • GH/IGF-1 axis and sleep architecture

Compounds that recur in this literature

Research context only — what each compound has been studied for in published work, not what it does for anyone. Independently tested by Janoshik Analytical.

BPC-157

Research vial

The gut-origin peptide studied across barrier, ulcer, tendon and gut-brain-axis models. For a systems reader it is the compound that connects the gut-immune and musculoskeletal literatures.

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Selank

Research vial

A tuftsin analogue with Russian clinical research on anxiety and stress, and animal work on IL-6 and interferon gene expression. It bridges the stress-axis and immune literatures.

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Glutathione

Research vial

The master intracellular antioxidant. A human study reported that liposomal oral glutathione raised body stores; it is studied in mucosal immunity, NK-cell activity and exercise oxidative stress.

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SS-31

Research vial

The cardiolipin-binding peptide that preserves inner-membrane structure and ATP recovery in ischaemic models, with a 2025 US accelerated approval in a rare mitochondrial disease. The hard-endpoint end of mitochondrial research.

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KPV

Research vial

α-MSH tripeptide studied in colitis and keratinocyte models for NF-κB suppression. It is the anti-inflammatory signalling reference across gut and skin literatures.

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Vitality Max

Research set

The mitochondrial and redox research set, adding glutathione to SS-31, MOTS-c and NAD+.

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Ordering in South Africa

Functional-medicine practices order broadly and often, so most orders clear the R2,500 free-shipping line. Dispatch is same-day from Johannesburg on weekday orders paid before noon; The Courier Guy reaches Gauteng next business day and the coastal metros in one to two. A multi-practitioner clinic can send parcels to a PUDO locker at checkout to keep reception clear. Every vial's certificate is linked from its product page, and storage guidance per compound is published alongside.

Questions before ordering: WhatsApp 076 680 0306 or 072 926 7667. Delivery detail for your city: research peptides in Cape Town.

Questions functional-medicine practitioners ask

Why do you group compounds by axis?

Because that is how the literature actually connects: one compound in several models. The product pages carry a ten-axis evidence profile with a stated rubric so the grading is explicit.

Do Selank and Semax have human data?

Yes. Both are registered medicines in Russia with clinical studies. We treat Russian clinical research as human evidence and say where it comes from.

Can a practice order for research?

Yes. Compounds are supplied for laboratory research with an independent Janoshik Analytical certificate of identity and HPLC purity. They are not for administration to patients, and we do not provide protocols.

What about hormone and incretin compounds?

They are listed on the site with their own research pages. This page covers the gut, stress, redox and GH-axis literature.

RESEARCH READING

RESEARCH SETS

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