Nootropic & neuropeptide research compounds
Vasopressin (AVP)
Also known as arginine vasopressin · AVP · antidiuretic hormone · ADH
The posterior-pituitary nonapeptide that controls water balance and blood pressure, and a central regulator of social and anxiety-related behaviour.
In 60 seconds
Registered medicine (vasodilatory shock, diabetes insipidus); intranasal research in human social behaviour. Clinical use carries vasoconstriction and fluid-balance risks; research doses in behavioural studies are small.
- Reviews vasopressin’s systemic antidiuretic and cardiovascular roles across species.
- Reviews oxytocin and vasopressin circuits in social behaviour and clinical research opportunities.
- Reviews evidence for oxytocin and vasopressin in human social cognition.
Mechanism
Peripherally, AVP acts at V2 (kidney) and V1a (vascular) receptors. Centrally, AVP neurons acting via V1a and V1b receptors modulate social recognition, pair-bonding and stress responses — research often paired with oxytocin.
Research status
Registered medicine (vasodilatory shock, diabetes insipidus); intranasal research in human social behaviour.
Key studies
Reviews vasopressin’s systemic antidiuretic and cardiovascular roles across species.
The Biology of Vasopressin — Biomedicines, 2021 · PMID 33477721
Reviews oxytocin and vasopressin circuits in social behaviour and clinical research opportunities.
Oxytocin, Vasopressin, and Social Behavior: From Neural Circuits to Clinical Opportunities — Endocrinology, 2022 · PMID 35863332
Reviews evidence for oxytocin and vasopressin in human social cognition.
Oxytocin, vasopressin, and human social behavior — Front Neuroendocrinol, 2009 · PMID 19505497
Reviews the V1b receptor’s role in social behaviour beyond the V1a receptor.
The vasopressin 1b receptor and the neural regulation of social behavior — Horm Behav, 2012 · PMID 22178035
Safety signals in the literature
Clinical use carries vasoconstriction and fluid-balance risks; research doses in behavioural studies are small.
Legal status (South Africa)
Not registered as a medicine for human use in South Africa (unless stated otherwise); research use only.
Related compounds we stock
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Comparisons
Questions
What is Vasopressin (AVP)?
The posterior-pituitary nonapeptide that controls water balance and blood pressure, and a central regulator of social and anxiety-related behaviour. Peripherally, AVP acts at V2 (kidney) and V1a (vascular) receptors. Centrally, AVP neurons acting via V1a and V1b receptors modulate social recognition, pair-bonding and stress responses — research often paired with oxytocin.
What is the research status of Vasopressin (AVP)?
Registered medicine (vasodilatory shock, diabetes insipidus); intranasal research in human social behaviour.
What safety signals are reported for Vasopressin (AVP)?
Clinical use carries vasoconstriction and fluid-balance risks; research doses in behavioural studies are small.
Does Living Water Labs stock Vasopressin (AVP)?
Not at present. Vasopressin (AVP) is profiled here for reference, with citations to the published literature. You can ask to be notified if we add it. Not registered as a medicine for human use in South Africa (unless stated otherwise); research use only.
More in Nootropic & neuro
Research reference only. This page summarises published literature; it is not medical advice and contains no guidance on human use. Products supplied by Living Water Labs are for laboratory research only.
