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Selank research peptide

Research Overview

Selank

Calm, Clear Focus

HPLC-verified 98%Batch CoAResearch use only

OVERVIEW

Selank (Calm, Clear Focus) is a research-grade peptide supplied by Living Water Labs for laboratory investigation. Calms anxiety, steadies mood and restores a sense of ease. Each batch is HPLC-verified to a minimum 98% purity with a batch-specific Certificate of Analysis. The summary below outlines documented mechanisms and study areas reported in the research literature.

Scientific name

Thr-Lys-Pro-Arg-Pro-Gly-Pro

Molecular weight

752.9 g/mol

Purity

99.3%

Vial size

10mg

DOCUMENTED RESEARCH AREAS

  • ▸Eases anxiety and tension
  • ▸Balanced, steady mood
  • ▸Calm without sedation
  • ▸Clearer, focused thinking
  • ▸Better stress resilience
  • ▸More restful sleep

MECHANISM OF ACTION

Selank is a synthetic heptapeptide analogue of the immunomodulatory peptide tuftsin. In rodent studies it is reported to modulate GABAergic and monoamine neurotransmission and the expression of brain-derived neurotrophic factor (BDNF), producing anxiolytic-like and cognitive effects in animal models without the sedation associated with benzodiazepines.

  • ▸Modulates GABAergic signalling and BDNF expression in animal brain
  • ▸Influences enkephalin degradation and monoamine systems in rodents
  • ▸Anxiolytic-like activity without benzodiazepine-type sedation in models

STUDY SUMMARIES

4 peer-reviewed references

Protein Pept Lett · 2018

Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity

A review of the molecular mechanisms proposed to underlie the anxiolytic-like activity of the heptapeptide Selank.

View on PubMed (PMID 30255741)

Behav Neurol · 2017

Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress

In a chronic-mild-stress rat model, Selank enhanced the anxiety-reducing effect of diazepam.

View on PubMed (PMID 28280289)

Bull Exp Biol Med · 2019

Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment

In rodents, Selank protected against ethanol-induced memory impairment.

View on PubMed (PMID 31625062)

Bull Exp Biol Med · 2022

Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats

In rats, Selank attenuated aversive behavioural signs of morphine withdrawal.

View on PubMed (PMID 36322304)

CITATIONS

  1. 1.Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity. Protein Pept Lett. 2018. PMID 30255741. pubmed.ncbi.nlm.nih.gov/30255741
  2. 2.Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress. Behav Neurol. 2017. PMID 28280289. pubmed.ncbi.nlm.nih.gov/28280289
  3. 3.Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment. Bull Exp Biol Med. 2019. PMID 31625062. pubmed.ncbi.nlm.nih.gov/31625062
  4. 4.Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats. Bull Exp Biol Med. 2022. PMID 36322304. pubmed.ncbi.nlm.nih.gov/36322304

Citations describe findings reported in the referenced preclinical, in-vitro or clinical literature. They are provided for research and educational purposes only and are not a therapeutic claim.

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All information is provided for research and educational purposes only and describes findings in preclinical/in-vitro literature. Not medical advice. Products are supplied strictly for research purposes — not for human consumption.

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