Nootropic & neuropeptide research compounds
Citicoline (CDP-Choline)
Also known as CDP-choline · cytidine diphosphate-choline
A naturally occurring intermediate in phosphatidylcholine synthesis, studied as a neuroprotective and cognitive compound.
In 60 seconds
Registered medicine in several countries (stroke, cognitive impairment) and a supplement elsewhere; evidence in stroke is debated. Reviews describe a favourable safety profile.
- A comprehensive pharmacological and clinical review of citicoline.
- A randomised trial measured memory function with citicoline in healthy older adults.
- A meta-analysis of citicoline in preventing and slowing dementia.
Mechanism
Citicoline supplies choline and cytidine for neuronal membrane phospholipids and influences acetylcholine, dopamine and glutamate systems.
Research status
Registered medicine in several countries (stroke, cognitive impairment) and a supplement elsewhere; evidence in stroke is debated.
Key studies
A comprehensive pharmacological and clinical review of citicoline.
Citicoline: pharmacological and clinical review, 2022 update — Rev Neurol, 2022 · PMID 36544369
A randomised trial measured memory function with citicoline in healthy older adults.
Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial — J Nutr, 2021 · PMID 33978188
A meta-analysis of citicoline in preventing and slowing dementia.
Is Citicoline Effective in Preventing and Slowing Down Dementia?-A Systematic Review and a Meta-Analysis — Nutrients, 2023 · PMID 36678257
A systematic review questioning citicoline’s benefit in stroke and brain injury.
Is aura around citicoline fading? A systemic review — Indian J Pharmacol, 2017 · PMID 28458415
Safety signals in the literature
Reviews describe a favourable safety profile.
Legal status (South Africa)
Not registered as a medicine for human use in South Africa (unless stated otherwise); research use only.
Related compounds we stock
Not stocked yet — get notified
Tell us you want Citicoline (CDP-Choline) and we’ll email you if we add it. Requests decide what we source next.
Not stocked yet
Get notified when we add Citicoline (CDP-Choline)
One email, only when it reaches the catalogue. Every request is counted when we choose what to stock next.
Comparisons
Questions
What is Citicoline (CDP-Choline)?
A naturally occurring intermediate in phosphatidylcholine synthesis, studied as a neuroprotective and cognitive compound. Citicoline supplies choline and cytidine for neuronal membrane phospholipids and influences acetylcholine, dopamine and glutamate systems.
What is the research status of Citicoline (CDP-Choline)?
Registered medicine in several countries (stroke, cognitive impairment) and a supplement elsewhere; evidence in stroke is debated.
What safety signals are reported for Citicoline (CDP-Choline)?
Reviews describe a favourable safety profile.
Does Living Water Labs stock Citicoline (CDP-Choline)?
Not at present. Citicoline (CDP-Choline) is profiled here for reference, with citations to the published literature. You can ask to be notified if we add it. Not registered as a medicine for human use in South Africa (unless stated otherwise); research use only.
More in Nootropic & neuro
Research reference only. This page summarises published literature; it is not medical advice and contains no guidance on human use. Products supplied by Living Water Labs are for laboratory research only.
