Short peptide bioregulators
Vesugen (Lys-Glu-Asp)
Also known as KED · Lys-Glu-Asp
A synthetic tripeptide bioregulator associated with vascular endothelium in the Khavinson programme.
In 60 seconds
Cell, animal and small uncontrolled human studies from one research group. No independent human safety data.
- Vesugen stimulated the proliferation marker Ki-67 in vascular endothelial cultures from young and old animals.
- Compared antihypoxic properties of vilon, epitalon, vesugen and pinealon in a hypobaric-hypoxia model.
- Reviews the developers’ work on KED (Lys-Glu-Asp) and neurogenesis-related genes in Alzheimer’s models.
Mechanism
Reported to stimulate proliferation markers (Ki-67) in vascular endothelial cell cultures from aged animals and to influence neuronal differentiation genes; as with related peptides, attributed to gene-expression regulation.
Research status
Cell, animal and small uncontrolled human studies from one research group.
Key studies
Vesugen stimulated the proliferation marker Ki-67 in vascular endothelial cultures from young and old animals.
[Epigenetic aspects of peptidergic regulation of vascular endothelial cell proliferation during aging] — Adv Gerontol, 2014 · PMID 25051766
Compared antihypoxic properties of vilon, epitalon, vesugen and pinealon in a hypobaric-hypoxia model.
[Investigation of antihypoxic properties of short peptides] — Adv Gerontol, 2008 · PMID 18546825
Reviews the developers’ work on KED (Lys-Glu-Asp) and neurogenesis-related genes in Alzheimer’s models.
Peptide KED: Molecular-Genetic Aspects of Neurogenesis Regulation in Alzheimer’s Disease — Bull Exp Biol Med, 2021 · PMID 34173097
Safety signals in the literature
No independent human safety data.
Legal status (South Africa)
Not registered medicines in South Africa; research use only.
Related compounds we stock
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Comparisons
Questions
What is Vesugen (Lys-Glu-Asp)?
A synthetic tripeptide bioregulator associated with vascular endothelium in the Khavinson programme. Reported to stimulate proliferation markers (Ki-67) in vascular endothelial cell cultures from aged animals and to influence neuronal differentiation genes; as with related peptides, attributed to gene-expression regulation.
What is the research status of Vesugen (Lys-Glu-Asp)?
Cell, animal and small uncontrolled human studies from one research group.
What safety signals are reported for Vesugen (Lys-Glu-Asp)?
No independent human safety data.
Does Living Water Labs stock Vesugen (Lys-Glu-Asp)?
Not at present. Vesugen (Lys-Glu-Asp) is profiled here for reference, with citations to the published literature. You can ask to be notified if we add it. Not registered medicines in South Africa; research use only.
More in Bioregulators
Research reference only. This page summarises published literature; it is not medical advice and contains no guidance on human use. Products supplied by Living Water Labs are for laboratory research only.
