SS-31 (elamipretide) is a cell-permeable tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2) that concentrates in the inner mitochondrial membrane and binds cardiolipin, the phospholipid that organises the electron-transport chain.
SS-31 (D-Arg-Dmt-Lys-Phe-NH2 (elamipretide)) is a research-grade peptide supplied by Living Water Labs for laboratory investigation. Mitochondria-targeted tetrapeptide (elamipretide), 10 mg lyophilised powder per vial.. Each published certificate is an independent Janoshik Analytical report naming the compound and its HPLC purity; certificates not yet published can be requested. The summary below outlines documented mechanisms and study areas reported in the research literature.
Scientific name
D-Arg-Dmt-Lys-Phe-NH2 (elamipretide)
Molecular weight
639.8 g/mol
Vial size
10mg
SS-31 (elamipretide) is a cell-permeable tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2) that concentrates in the inner mitochondrial membrane and binds cardiolipin, the phospholipid that organises the electron-transport chain. In injury models this is reported to stabilise cristae structure and restore ATP production; in 2025 elamipretide received US accelerated approval for muscle strength in Barth syndrome, a rare cardiolipin disorder.
J Am Soc Nephrol · 2013
In an ischaemic kidney model, SS-31 preserved cristae and speeded ATP recovery by interacting with cardiolipin.
View on PubMed (PMID 23813215)Int J Mol Sci · 2025
Reviews elamipretide’s structure, cardiolipin-binding mechanism and research applications.
View on PubMed (PMID 39940712)Drugs · 2026
Summarises the September 2025 US accelerated approval of elamipretide for muscle strength in Barth syndrome.
View on PubMed (PMID 41335372)Citations describe findings reported in the referenced preclinical, in-vitro or clinical literature. They are provided for research and educational purposes only and are not a therapeutic claim.
All information is provided for research and educational purposes only and describes findings in preclinical/in-vitro literature. Not medical advice. Products are supplied strictly for research purposes — not for human consumption.
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Step-by-step guides — reconstitution, dosing, storage, handling and CoAs.
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Third-party lab documentation confirming a batch’s identity and purity.
Explore →High-performance liquid chromatography — the assay behind the purity figure on every published certificate.
Explore →Dissolving a lyophilised peptide in bacteriostatic water to a target concentration.
Explore →Freeze-dried to a stable powder for cold, dark, long-term storage.
Explore →Sterile water with 0.9% benzyl alcohol, used to reconstitute peptides.
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