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Ipamorelin research peptide

Research Overview

Ipamorelin

Lean Muscle & Deep Sleep

HPLC-verified 98%Batch CoAResearch use only

OVERVIEW

Ipamorelin (Lean Muscle & Deep Sleep) is a research-grade peptide supplied by Living Water Labs for laboratory investigation. Naturally lifts growth hormone for leaner body and better recovery. Each batch is HPLC-verified to a minimum 98% purity with a batch-specific Certificate of Analysis. The summary below outlines documented mechanisms and study areas reported in the research literature.

Scientific name

Aib-His-D-2-Nal-D-Phe-Lys-NH2

Molecular weight

711.9 g/mol

Purity

99.0%

Vial size

10mg

DOCUMENTED RESEARCH AREAS

  • ▸Boosts natural growth hormone
  • ▸Builds lean muscle
  • ▸Accelerates fat loss
  • ▸Deeper, better sleep
  • ▸Faster recovery
  • ▸Gentle, selective action

MECHANISM OF ACTION

Ipamorelin is a synthetic pentapeptide that selectively binds the growth-hormone-secretagogue receptor (the ghrelin receptor). In animal studies it stimulates pulsatile growth-hormone release from the pituitary with high selectivity — reported not to meaningfully raise cortisol or prolactin — which is why it is used as a research tool for growth-hormone-axis physiology.

  • ▸Selective agonist of the growth-hormone-secretagogue (ghrelin) receptor
  • ▸Stimulates pituitary growth-hormone release in preclinical models
  • ▸Reported minimal effect on cortisol/prolactin versus earlier secretagogues

STUDY SUMMARIES

3 peer-reviewed references

Eur J Endocrinol · 1998

Ipamorelin, the first selective growth hormone secretagogue

The characterisation study describing ipamorelin as the first GH secretagogue to release growth hormone with a selectivity comparable to GHRH in animals.

View on PubMed (PMID 9849822)

Growth Horm IGF Res · 2001

The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation

In a glucocorticoid-treated rat model, ipamorelin counteracted the steroid-induced decrease in bone formation.

View on PubMed (PMID 11735244)

Physiol Behav · 2024

Growth hormone secretagogue receptor 1a agonists, anamorelin and ipamorelin, inhibit cisplatin-induced weight loss

In a preclinical study, GHS-R1a agonists including ipamorelin reduced cisplatin-induced weight loss in animals.

View on PubMed (PMID 39043357)

CITATIONS

  1. 1.Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998. PMID 9849822. pubmed.ncbi.nlm.nih.gov/9849822
  2. 2.The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation. Growth Horm IGF Res. 2001. PMID 11735244. pubmed.ncbi.nlm.nih.gov/11735244
  3. 3.Growth hormone secretagogue receptor 1a agonists, anamorelin and ipamorelin, inhibit cisplatin-induced weight loss. Physiol Behav. 2024. PMID 39043357. pubmed.ncbi.nlm.nih.gov/39043357

Citations describe findings reported in the referenced preclinical, in-vitro or clinical literature. They are provided for research and educational purposes only and are not a therapeutic claim.

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All information is provided for research and educational purposes only and describes findings in preclinical/in-vitro literature. Not medical advice. Products are supplied strictly for research purposes — not for human consumption.

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