Epitalon vs Vilon
Both are Khavinson-programme synthetic bioregulators. Epitalon (Ala-Glu-Asp-Gly) is tied to pineal research and telomerase; vilon (Lys-Glu) to thymic and immune research.
Epitalon
Epitalon (epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) modelled on the pineal peptide epithalamin.
BEST STUDIED FOR
Telomerase and pineal-ageing models
R549View product →
Vilon
A synthetic dipeptide (Lys-Glu) from the Khavinson bioregulator programme, studied for immune and chromatin effects in cell and animal models.
BEST STUDIED FOR
Bioregulators
Read the cited profile →
Side by side · to buy
Price, purity and dispatch
| Compare | Epitalon10mg | Vilon |
|---|---|---|
| Price | R549 | — |
| Cost per mg | R54.9 / mg | — |
| Purity (Janoshik) | On request | — |
| Stock | Restocking | — |
| Dispatch | When restocked | — |
| Certificate | Request CoA | — |
| Literature | 4 papers → | — |
| Research focus | Telomerase and pineal-ageing models | Bioregulators |
| Notify me | Read the cited profile |
Prices are read live from the catalogue. Cost per mg is the vial price over its stated mg. Purity is shown only where the certificate is published. Every compound is supplied for laboratory research only.
SIDE BY SIDE
| Epitalon | Vilon | |
|---|---|---|
| The key difference | Pineal-associated tetrapeptide | Thymus-associated dipeptide |
| Class | Bioregulators | Bioregulators |
| Mechanism | Epitalon (epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) modelled on the pineal peptide epithalamin. | Its developers report that Vilon "deheterochromatinises" aged chromatin in cultured lymphocytes and modulates gene expression (including in heart tissue and splenocyte IL-2), effects attributed to direct DNA/chromatin interaction of short peptides. |
| Status | A synthetic tetrapeptide from the Khavinson bioregulator programme; not an approved medicine. | Cell and animal studies, almost all from one research group; no independent clinical trials. |
| Reported safety signals | Human data are limited to small studies, mostly from one research group. | No independent human safety data. |
| A key study | In cultured human somatic cells, epithalon induced telomerase activity and elongation of telomeres. (Bull Exp Biol Med 2003, PMID 12937682) | In lymphocytes from older people, Vilon was reported to unroll condensed (heterochromatic) chromatin in vitro. (Biogerontology 2004, PMID 15105581) |
WHEN TO RESEARCH WHICH
Epitalon for pineal and telomere models; vilon for immune models. Both are discussed here strictly as research compounds; nothing on this page is medical advice or a dosing guide.
REFERENCES (PUBMED)
- [Epitalon] Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells — Bull Exp Biol Med 2003. PMID 12937682
- [Epitalon] Peptide promotes overcoming of the division limit in human somatic cell — Bull Exp Biol Med 2004. PMID 15455129
- [Epitalon] Effect of regulatory peptides on gene transcription — Bull Exp Biol Med 2003. PMID 14666197
- [Vilon] Bioregulator Vilon-induced reactivation of chromatin in cultured lymphocytes from old people — Biogerontology 2004. PMID 15105581
- [Vilon] Studies of the effects of Vilon and Epithalon on gene expression in mouse heart using DNA-microarray technology — Bull Exp Biol Med 2002. PMID 12360356
- [Vilon] In vitro effect of short peptides on expression of interleukin-2 gene in splenocytes — Bull Exp Biol Med 2002. PMID 12447482
FREQUENTLY ASKED
What is the difference between Epitalon and Vilon?
Both are Khavinson-programme synthetic bioregulators. Epitalon (Ala-Glu-Asp-Gly) is tied to pineal research and telomerase; vilon (Lys-Glu) to thymic and immune research.
What is the regulatory status of Epitalon and Vilon?
Epitalon: A synthetic tetrapeptide from the Khavinson bioregulator programme; not an approved medicine. Vilon: Cell and animal studies, almost all from one research group; no independent clinical trials.
What safety signals have been reported?
Epitalon: Human data are limited to small studies, mostly from one research group. Vilon: No independent human safety data.
Which studies is this comparison based on?
For Epitalon: “Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells” (PMID 12937682); “Peptide promotes overcoming of the division limit in human somatic cell” (PMID 15455129); “Effect of regulatory peptides on gene transcription” (PMID 14666197). For Vilon: “Bioregulator Vilon-induced reactivation of chromatin in cultured lymphocytes from old people” (PMID 15105581); “Studies of the effects of Vilon and Epithalon on gene expression in mouse heart using DNA-microarray technology” (PMID 12360356); “In vitro effect of short peptides on expression of interleukin-2 gene in splenocytes” (PMID 12447482).
MORE COMPARISONS
All products supplied for research purposes only. Not for human consumption.
In stock · ships from South Africa
In stock now
Supplied for laboratory research only · not for human use